Sterlitech HP4750 Supplement
HP4750
ASSEMBLY & OPERATION
MANUAL
1. INTRODUCTION ........................................................................................ 1
2. BEFORE ASSEMBLY............................................................................... 2
3. STIRRED CELL ASSEMBLY .....................................................................3
4. OPERATION OF THE HP4750 STIRRED CELL .................................. 6
5. HP4750 EXAMPLE SYSTEM CONFIGURATION ............................... 8
6. ACCESSORY AND SPARE PART ORDERING INFORMATION ......... 9
7. O-RING CHEMICAL COMPATIBILITY...................................................10
8. RETURN MATERIAL ORDER PROCEDURE ......................................... 11
9. WARRANTY .............................................................................................. 11
10. TECHNICAL ASSISTANCE.................................................................... 11
APPENDIX 1: COMPRESSION CONNECTIONS ..................................... 12
APPENDIX 2: MEMBRANE CUTTING AND CONDITIONING .............. 13
APPENDIX 3: PRECONDITIONING MEMBRANE DISC FILTERS......... 14
APPENDIX 4: HP4750 BIBLIOGRAPHY .................................................. 15
APPENDIX 5: BENCH SCALE FILTRATION PRODUCTS...................... 16
CONTENTS
1. INTRODUCTION
The HP4750 Stirred Cell is a high-pressure, chemically resistant stirred cell that performs
a wide variety of membrane separations. With a maximum pressure rating of 1000 psig
(69 bar), the HP4750 Stirred Cell is ideally suited for reverse osmosis (RO) filtration,
nanofiltration (NF), ultrafiltration (UF), and microfiltration (MF) separations. Stainless steel
(316L) construction and chemically resistant components make the HP4750 Stirred Cell an
ideal choice to filter aqueous and non-aqueous solutions.
Table 1 outlines the operational parameters and technical specifications of the HP4750
Cell.
Prior to operating or servicing this device, this manual must be read and understood.
Table 1: HP4750 Features and Technical Specification
Parameter Description
Membrane Size 47-49 mm diameter (1.93 inches)
Active Membrane Area 14.6 cm2(2.26 in2)
Processing Volume 300 mL
Hold-Up Volume 1 mL
Maximum Pressure 69 bar (1000 psig)
Maximum Temperature 121 °C (250 °F) at 55 bars (800 psig)
Maximum Torque Setting for Nuts 20 ft-lbs
pH Range Membrane Dependant
Connections
Permeate Outlet ⁄ inch diameter 316L SS tubing
Pressure Inlet ¼ inch FNPT
Wetted Materials of Construction
Cell Body 316L Stainless Steel
O-Rings Buna-N, others available as options
Gasket Buna-N, others available as options
Stir Bar PTFE-coated magnet
Dimensions
Cell Diameter 5.1 cm (2.0 inches)
Cell Height 22.4 cm (10.0 inches)
Autoclavable Ye s
Sterlitech Corporation | HP4750 Cell Manual
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2. BEFORE ASSEMBLY
HP4750 Cell Manual | Sterlitech Corporation 2
1. Stainless steel cell body
2. Cell Top
3. Cell Bottom
4. Cell Top Coupling
5. Cell Bottom Coupling
6. Porous Stainless Steel Membrane Support Disk
7. 2 O-rings
8. Top Gasket
9. Permeate Tube
10. Stir Bar Assembly
11. Stir Bar Retriever
Verify that the stirred cell was shipped complete, intact, and undamaged. The complete
set of stirred cell parts is found in Figure 1 below.
Figure 1: HP4750 Components
Sterlitech Corporation | HP4750 Cell Manual
3
To assemble the HP4750 stirred cell:
1. Wet the O-rings with a small amount of
water or the fluid to be processed.
Note: HP4750 Stirred Cells are shipped
with Buna O-rings and gaskets by default;
other materials such as Viton and PTFE are
available as options. Table 3 outlines O-ring
and gasket material compatibility.
2. Insert the O-rings in the bottom of the cell
body (Photo 1 & 2). Check to be certain
that the O-rings it properly in the grooves.
3. Place a piece of precut membrane over
the center O-ring. The membrane should
be installed with the active side toward
the cell reservoir. In general, membranes
coated on substrate have a shiny, active
side and a dull, substrate side (Photo 3).
4. Place the stainless steel porous membrane
support disk on top of the membrane to
hold the membrane in place (Photo 4).
Note: If you cut your own membranes, the
stainless steel porous disk can be used as a
template. See Appendix 3 for more details.
3. STIRRED CELL ASSEMBLY
After verifying that all of the necessary components were shipped and present, you can
begin the assembly of the stirred cell.
Photo 1: Outer Ring Insertion
Photo 2: Inner Ring Insertion
Photo 3: Membrane Filter Insertion
Photo 4: Membrane Support Disc Insertion
HP4750 Cell Manual | Sterlitech Corporation 4
5. Fit the cell bottom onto the cell body,
aligning the circular groove with the
circular ridge on the bottom of the cell
body (Photo 5).
6. Use the 3-inch high pressure coupling to
clamp the cell bottom to the cell body.
Tighten the high pressure coupling with
16 foot pounds of torque for 1000 psig (69
bar) operation (Photo 6).
7. Insert Permeate Tube into side of cell
body, tighten using a wrench (Photo 7).
Note: The HP4750 uses Swagelok connection
fittings. More detailed instructions, information
and images of the fittings can be found in
Appendix 1.
8. Insert the Stir bar assembly by lowering
it into the cell with the stir bar retriever
(Photo 8). Figure 2 shows the correct
position of the Stir Bar Assembly. After the
assembly is in place, pour the solution to
be filtered into the Cell Body.
Figure 2: Proper Stir Bar Position
Photo 5: Cell Bottom Assembly
Photo 6: Bottom Clamp Assembly
Photo 7: Permeate Tube Installation
Photo 8: Stir Bar Insertion w/ Stir Bar Retriever
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5
9. Insert the gasket on the top of the Cell
Body, making sure it fits properly in the
grooves (Photo 9).
10. Use the 2-inch high pressure coupling to
clamp the cell top to the cell body (Photo
10). Tighten the high pressure coupling
with 16 foot pounds of torque for 1000 psig
(69 bar) operation (Photo 11). After both
clamps are properly attached, the HP4750
Stirred Cell should be centered on top of a
magnetic stirrer.
Photo 9: Gasket Installation
Photo 10: Cell Top Attachment
Photo 11: Cell Top Clamp
HP4750 Cell Manual | Sterlitech Corporation 6
4. OPERATION OF THE HP4750 STIRRED CELL
1. Attach a high pressure hose (sold
separately, Sterlitech Part Number: 1151427)
to the fitting on the Cell Top (Photo 12).
2. Connect the other end of the hose to the
pressure regulator assembly on the inert
gas supply or the compressed air supply.
The compressed air or inert gas source
selected will determine pressure regulator
(sold separately, Sterlitech Part Number:
1144026 style and pressure requirements
(Photo 13).
3. Place a Permeate Collection Vessel (user
supplied) under the Permeate Tube (Photo
14).
4. Turn on the magnetic stirrer (sold
separately, Sterlitech Part Number 1144030
or 1144031) to start the motion of the Stir
Bar Assembly (Photo 15).
5. Begin filtration by gradually pressurizing
the HP4750 Stirred Cell, checking for
leaks. Foreign material on the surface of
the seals and insucient tightening of
the clamps are most common causes for
leakage.
Note: Preconditioning the membranes before
use will ensure consistent performance. See
Appendix 3 for more details.
Photo 12: High Pressure Hose Attachment
Photo 13: Pressure Regulator Connection
Photo 14: Permeate Collection Vessel
Photo 15: Magnetic Stirrer
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6. Upon completion of filtration, turn o
the pressure source and depressurize
the unit by the pressure relief valve
(sold separately, Sterlitech Part Number:
1155893) (Photo 16).
CAUTION: Do not depressurize the HP4750
Stirred Cell by loosening the couplings.
7. Once it is depressurized and empty, the
HP4750 Stirred Cell can be cleaned with
a variety of cleaners, including detergents,
solvents, caustic, acid, enzyme cleaners,
etc.
Note: Choice of the appropriate cleaning
regime should also consider the compatibility
of the gasket and O-ring material. A section of
O-ring chemical compatibilities is presented
on page 10.
Photo 16: Pressure Relief Valve
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