SIS M250 User manual

SIS MACHINES

TECHNICAL OPERATING MANUAL_M250/M250MA_v2.2

This operating manual is downloadable from https://siselectromed.com/

Due to periodic revisions, always check that you are reading the most up to

date version of this manual.

PLEASE READ THIS MANUAL CAREFULLY BEFORE USING THE SIS

EQUIPMENT FOR CORRECT AND SAFE OPERATION.

Page . SIS ANUFACTURING LTD, NZ. JULY 2020.

SIS MACHINE M250/M250MA MODEL OPERATING MANUAL

CONTENTS

SECTION PAGE

DELIVERY AND UNPACKING_ _ _ __ _ _ _ _ _ _ _ _ _ _ _ _ 4

WARNING FOR BIOLOGICAL APPLICATIONS _ _ _ _ _ _ _ 4

DEVICE DESCRIPTION _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ 4

POWER SOURCE _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ 5

ELECTRODE CABLE CONNECTION _ _ _ _ _ _ _ _ _ _ _ _ 5

KEYPAD CONTROLS AND OPERATION _ _ _ _ _ _ _ _ _ _ 6-7

APPLICATIONS_ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ 6

SIS electrodes_ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ 7-8

Connection of electrode cable to electrodes _ _ _ _ _ _ 7

Infection treatments_ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ 9

Direct Current (DC) Electrotherapy _ _ _ _ _ _ _ _ _ _ _ 10-11

DC electro-acupuncture_ _ _ _ _ _ _ _ _ _ _ _ _ _ 11

DC battlefield electro-acupuncture (BFA)_ _ _ _ _ 11-12

Transcranial DC stimulation (tDCS)_ _ _ _ _ _ _ _ 12

Low intensity DC current microcurrent electrical

neuromuscular stimulation ( ENS) _ _ _ _ _ _ _ _

12-13

Scar pain treatment _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ 13

Ionic solution medication iontophoresis_ _ _ _ _ _ 13-14

Cell apoptosis stimulation_ _ _ _ _ _ _ _ _ _ _ _ _ 14-15

Laboratory and research use_ _ _ _ _ _ _ _ _ _ _ 15

AUDIO AND VISUAL ALERTS_ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ 16

Page 2. SIS ANUFACTURING LTD NZ. JULY 2020.

SIS MACHINE M250/M250MA MODEL OPERATING MANUAL

ELECTROTHERAPY ELECTRODE↔SKIN CONTACT _ _ _ 17-18

CONTRAINDICATIONS AND SAFETY_ _ _ _ _ _ _ _ _ _ _ _ 19

EDICAL DISCLAI ER _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ 20

WATER TREAT ENT_ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _21

AINTENANCE _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ 22

WARRANTY_ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _23

Returns, Disposal _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _24

DEVICE SPECIFICATIONS _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ 25

ANUFACTURER'S DECLARATION_ _ _ _ _ _ _ _ _ _ _ _ _26

Page 3. SIS ANUFACTURING LTD NZ. JULY 2020.

SIS MACHINE M250/M250MA MODEL OPERATING MANUAL

DELIVERY AND UNPACKING

Please unpack the shipping package carefully and inspect contents

immediately on receipt. Check that all ordered equipment is included in the

shipping box and notify SIS anufacturing Ltd New Zealand immediately of

any missing items from your order.

Visible damage or tampering to shipping boxes must be recorded before

signing the delivery receipt. Please take photographs of any received

damaged items. Report the damage or tampering immediately to the shipping

carrier. You must also notify SIS anufacturing Ltd immediately of any

received damaged or tampered items or of any lost shipments.

WARNING FOR BIOLOGICAL APPLICATIONS

THE SIS ACHINES ODELS 250/ 250 A ARE ELECTRONICALLY

CALIBRATED WITH EXTRE E PRECISION FOR THERAPEUTIC

BIOLOGICAL ELECTRICAL STI ULATION IN CO BINATION WITH THE

SIS SILVER-NYLON ELECTRODES. USE OF OTHER ELECTRODES CAN

CAUSE ADVERSE AND UNPREDICTABLE BIOLOGICAL EFFECTS. FOR

OTHER BIOLOGICAL ELECTRICAL STI ULATION APPLICATIONS, IF SIS

SILVER-NYLON ELECTRODES ARE NOT USED, ONLY USE SURFACE,

INSERTED OR I PLANTED ELECTRODES APPROVED FOR BIOLOGICAL

CONTACT AND EDICAL/THERAPEUTIC APPLICATIONS. READ THE

CONTRAINDICATIONS AND SAFETY INSTRUCTIONS IN THIS ANUAL

BEFORE USING THIS EQUIP ENT.

DEVICE DESCRIPTION

The SIS machines 250/ 250 A models are designed for electromedical,

nanoampere to low milliampere direct current (DC) electrotherapy

applications, and for low intensity (amperage) DC silver iontophoresis

stimulation (SIS) when used with SIS electrodes. The 250 A model can be

used for liquid medication intophoresis, and for cell apoptosis stimulation.

The 250/ 250 A models are also designed for use as a nanoampere to

low milliampere ( 250 A only) constant current generators for non-medical,

non-therapeutic, non-diagnostic, research, laboratory and experimental

purposes, including Life Sciences, and water treatment.

Page 4. SIS ANUFACTURING LTD NZ. JULY 2020.

SIS MACHINE M250/M250MA MODEL OPERATING MANUAL

. POWER SOURCE

The 250/ 250 A is powered by replaceable AAA type batteries.

Rechargeable batteries can be used and do not compromise the correct

function of the device. Refer to section 15. DEVICE SPECIFICATIONS for

further information.

Do not use zinc-carbon batteries that can leak and damage the device.

. . INSERTING AAA BATTERIES

A. POWER OFF the device if it is operating.

B. Remove the shockproof silicon cover from the casing.

C. Remove the battery compartment cover.

D. Insert 3×AAA batteries. Ensure correct polarity of the batteries—follow

the battery diagram and polarity symbols inside the battery

compartment.

E. Replace the battery compartment cover.

F. Replace the shockproof silicon cover over the casing.

2. ELECTRODE CABLE CONNECTION

2. . CONNECTION OF ELECTRODE CABLE (HARNESS)

Unplug the Seal Cap from the connection socket (Jack) in the top end panel

of the device. Insert the cable connector plug all the way into the connection

socket. Screw tighten the Locking Ring on the cable connector plug to the

socket; DO NOT use excessive force.

2.2. CABLE TESTING

Perform a cable connection and integrity test from the CABLE TEST screen

before each application.

Page 5. SIS ANUFACTURING LTD NZ. JULY 2020.

SIS MACHINE M250/M250MA MODEL OPERATING MANUAL

3. KEYPAD CONTROLS AND OPERATION

POWER

ON OFF

Power device ON, 2 seconds hold.

Power device OFF, 5 seconds hold.

ain

Operating

Screen

Output CURRENT and STATUS displayed

PROGRAM Access ain

enu

scroll

through ain

enu options

EXIT

PROGRAM

to select

Return to ain Operating Screen

STIM DATA

Output Current and Voltage

and measured bioelectric

data

PROGRAM

or 

return to

ain enu

STATISTICS Electrode stimulation

efficiency data

CABLE TEST

Instructions

PROGRAM

Instructions 2

PROGRAM

Result:

PASSED

FAILED

DISPLAY



AUTO-OFF (DEFAULT) or

ALWAYS ON

TIMER Session duration data

MONITORING 

AUTO (DEFAULT) or OFF

POLARITY 

AUTO (DEFAULT) or OFF

ABOUT Information about device

DISPLAY

Sound turned ON or OFF, 2 seconds hold.

OLED display turned ON or OFF, 1 second hold, when DISPLAY set to

AUTO-OFF (DEFAULT).

The default device settings after powered on are OLED display and sound

turned on.

Page 6. SIS ANUFACTURING LTD NZ. JULY 2020.

SIS MACHINE M250/M250MA MODEL OPERATING MANUAL

If no keypad input is detected during normal STATUS: OK operation and the

AUTO-OFF default DISPLAY setting has not been changed to ALWAYS ON,

then the display turns off after 2 minutes for power saving.

At any time when the menu is accessed, if no user input is detected after 2

minutes, the device automatically powers off.

The red BATTERY CHARGE LED flashes every 5 seconds while the device

is operating; the LED is not under user control.

APPLICATIONS

4. SIS electrodes

NOTE: Position and secure the SIS electrodes to the body first, and then

connect the SIS electrode cable to the two SIS electrode wires.

NOTE: Read and follow the INSTRUCTIONS FOR USE (IFU) on the IFU card

included in each SIS electrode pack.

4. . Electrode size

4. . . INTERNAL INFECTIONS

The SIS (+)positive electrode must completely 'cover' a target internal organ

or other anatomical structure or area. The electrode must be at least the

same size or slightly larger than the target internal organ or other anatomical

structure as it would be seen two dimensionally in a diagnostic X-ray/CAT

scan/ RI scan/ultrasound taken from the position and anatomical plane of

the electrode on the body surface.

The SIS (-)return electrode should be (approximately) the same size or larger

than the SIS (+)positive electrode.

4. .2. SURFACE INFECTIONS

Use an SIS electrode size that most closely matches the dimensions of the

opposite sides of the area of the infection, where the electrodes will be

positioned. For example, for an area of infection that can be totally contained

within a 2cm×10cm rectangle, the 4.75cm diameter⌀ round SIS electrodes

should be applied next to the 2cm length sides of the infected area, or the

10cm×15cm SIS electrodes should be applied across the 10cm length sides.

Page 7. SIS ANUFACTURING LTD NZ. JULY 2020.

SIS MACHINE M250/M250MA MODEL OPERATING MANUAL

NOTE: Do not use over-sized SIS electrodes. The 250/ 250 A can more

accurately monitor electrode↔skin contact the smaller the electrode size.

4.2. Securing SIS electrodes

The contact of the entire surface of an electrode placed onto non-damaged

skin should be as uniform as possible to surface anatomy geometry.

NOTE: The silver-nylon side of an SIS electrode is the active surface that

contacts the body.

Use adhesive fixation tape, stretch strap, bandages or other emergency

means to secure the electrode to the body; adhesive tape should extend

beyond all edges of the electrode.

! IMPORTANT INFORMATION:

RECOMMENDED ELECTRODE LIFETIME FOR SEVERE INFECTION :

SIS (+)POSITIVE (RED WIRED) ELECTRODE: 2-24 HOURS

SIS (-)RETURN (BLACK WIRED) ELECTRODE: 2-48 HOURS

4.3. Connection of electrode cable to electrodes

●The SIS electrode that is connected to the red wire of the electrode

harness is the SIS (+)positive electrode.

●The SIS electrode that is connected to the black wire of the electrode

harness is the SIS (-)return electrode.

Insert the two gold metal 'banana plugs' at the ends of the black and red wires

of the electrode cable into the two white plastic connectors at the ends of the

SIS electrode wires; insert the 'banana plugs' all the way in until they are no

longer visible.

NOTE: Do not tape the connections of the electrode cable to the electrode

wires as doing so can cause excessive mechanical force on the cable

connection to the electro-stimulator.

Page 8. SIS ANUFACTURING LTD NZ. JULY 2020.

SIS MACHINE M250/M250MA MODEL OPERATING MANUAL

5. Infection treatments

! NOTE: The SIS machines 250/ 250 A can be targeted at almost any

infected anatomical structure or location. However, the devices cannot

determine the type of microbe(s) present; standard diagnostics and

differentiating information based on anatomical location, clinical signs,

presentation and/or laboratory testing must be applied.

5. . Electrode positioning

Diagrams of typical SIS electrode positionings for common infections are

available from: https://siselectromed.com/applications

NOTE: Avoid positioning electrodes over bones wherever possible.

5. . . INTERNAL INFECTION

A. Position the SIS (+)positive electrode onto intact skin skin directly over

the target infected organ or other anatomical structure.

B. Position the SIS (-)return electrode onto intact skin on the opposite

anatomical surface of the body to the SIS (+)positive electrode so that

the target infected organ or other anatomical structure is aligned bet ween

the two SIS electrodes.

5. .2. SURFACE INFECTION

A. Position the SIS (+)positive and (-)return electrodes on opposite side s

across and as close as possible to the target infected area ; do not place

electrodes on the infected area.

6. OUTPUT CURRENT

Adjust and PROGRA the output CURRENT for either a bacterial or

viral infection treatment:

➔B acteri al infection treatment or in vitro anti-bacterial effect: use the

default output CURRENT setting of 2.5 microAmps.

➔V iral infectio n treatment or an in vitro anti-viral effect: adjust the output

CURRENT to 7.5 microAmps.

Page 9. SIS ANUFACTURING LTD NZ. JULY 2020.

SIS MACHINE M250/M250MA MODEL OPERATING MANUAL

7. Direct Current (DC) Electrotherapy

The 250 ( 250 A) is a multirole microcurrent (and milliampere) electro-

stimulator.

If necessary, use the alligator clip adapters supplied with the SIS machine to

convert the 250/ 250 A electrode harness for connection to many other

electrodes. Insert the gold 'banana plugs' at the ends of the black and red

wires of the electrode harness into the plastic connector ends of the adapters.

7. . OUTPUT CURRENT POLARITY

(+)positive conventional current polarity is produced by the 250/ 250 A.

The black-wired ‘banana plug’ of the electrode cable is the conventional

(-)negative terminal (electrode). The red-wired ‘banana plug’ is the

conventional (+)positive terminal (electrode). That is, there is a galvanic cell

polarity current flow out of the device.

7.2. OUTPUT CURRENT POLARITY REVERSAL

The 250/ 250 A reverses the direction of current flow for 10 seconds

every 10 minutes. This function has been factory programmed for use of the

device with SIS electrodes, for removing electro-chemical debris from the

active surfaces of the electrodes resulting from the reduction and oxidation

reactions from the applied electric voltages.

NOTE: For most DC applications where other non-SIS electrodes are used,

this function is not required and can be turned OFF in the POLARITY screen.

7.3. ELECTRODE STIMULATION EFFICIENCY (ESE)

MONITORING

The 250/ 250 A monitors the contact of the SIS or other electrode(s) with

the body, or with the stimulation target for in vitro applications, in real-time

and statistically via complex measurement, logging and assessment

algorithms with self-adaptive AI aspects. The highly summarized logged ESE

data are shown in the STATISTICS screen.

ESE monitoring can be turned OFF for various DC electrotherapy applications

in the ONITORING screen. When ESE is disabled, no data are shown in the

STI DATA and STATISTICS screens.

Page 0. SIS ANUFACTURING LTD NZ. JULY 2020.

This manual suits for next models

Table of contents

Other SIS Medical Equipment manuals

SIS

SIS SIS W250 User manual

Popular Medical Equipment manuals by other brands

TekTone

TekTone Tek-CARE160 Installation and operation manual

NeuroMetrix

NeuroMetrix Quell 2.0 user manual

AMT

AMT XLR8 Quick reference guide

Medipost-Nutristoma

Medipost-Nutristoma MD300K2 instruction manual

EDAN

EDAN SONOTRAX Pro user manual

Restorative Therapies

Restorative Therapies RT300 Service guide

Gendex

Gendex Expert DC installation manual

Dexcowin

Dexcowin ADX4000W user manual

Libelium

Libelium MySignals user manual

Acelity

Acelity V.A.C.ULTA 4 user manual

Caputron

Caputron ActivaDose II tDCS quick start guide

FujiFilm

FujiFilm Sonart Features

Plinth 2000

Plinth 2000 93CDT Service manual

GE SENOGRAPHE 800T Operator's manual

GE Definium 5000 Operator's manual

Kanmed

Kanmed GE-1380 user manual

Huntleigh

Huntleigh FD1 Instructions for use

Stryker

Stryker SPR Plus Operation manual